Made famous by The Simpsons, fugu can be lethally poisonous due to its tetrodotoxin; therefore, it must be carefully prepared to remove toxic parts and to avoid contaminating the meat. The restaurant preparation of fugu is strictly controlled by law in Japan and several other countries, and only chefs who have qualified after three or more years of rigorous training are allowed to prepare the fish. Still, it's said to make one mean little sashimi dish.
Fugu contains lethal amounts of the poison tetrodotoxin in its inner organs, especially the liver, the ovaries, eyes, and skin. The poison, a sodium channel blocker, paralyzes the muscles while the victim stays fully conscious; the poisoned victim is unable to breathe, and eventually dies from asphyxiation. There is no known antidote for fugu poison. The standard treatment is to support the respiratory and circulatory systems until the poison is metabolized and excreted by the victim's body.
Celebrities are no strangers to changing their looks for a role. And in some instances, they have to get pretty extreme. From 500-calorie-a-day diets to drinking pints of ice cream, Actors and actresses know what it takes to change their bodies in preparation for a new film.
Charlize Theron is no stranger to gaining and losing weight for movie roles, as we remember her transformation in Monster. Charlize Theron gained close to 50 pounds for her role as Marlo in Tully. Theron said that “for the first time in my life I was eating so much processed foods and I drank way too much sugar. … I remember having to set my alarm in the middle of the night in order to just maintain the weight.”
You’re used Chris Hemsworth's hulk-like figure in Thor, but In the Heart of the Sea required a totally different diet. The movie required the cast members lose a ton of weight to make their stuck-at-sea plight more believable. Chris Hemsworth said there were days when all he ate was one boiled egg, a couple of crackers, and a celery stick.
Anne Hathaway wanted to get serious for her role in Les Misérables, as she was playing Fantine, a starving prostitute with tuberculosis. So Anne Hathaway went on a diet of “rabbit food” to drop 25 pounds. Hathaway explained her diet was essentially just starving herself, but she didn’t want to give details, as she doesn’t want to encourage anyone to copy her emaciated look. She did note that she “just had to stop eating for a total of 13 days shooting,” however. And at one point, her bones became so frail that she reportedly broke her arm.
Matthew McConaughey's portrayal of Ron Woodruff in Dallas Buyers Club, a man with HIV/AIDS, was spot-on, earning him the title of best actor at the Oscars. But it also required a serious physical transformation. Matthew McConaughey said he lost 38 pounds for the role. During filming, he said he lost a lot of energy from eating so little — and he hit plenty of plateaus along the way. Finally, with a strict diet, he got down to 143 pounds. And while he did cardio to help with the weight loss, he said it was 90% what he was eating and portion size.
Hilary Swank had to put on 23 pounds of pure muscle for her role as a boxer in Million Dollar Baby. The process doesn’t sound easy, however. “I started working out five hours a day — I had to eat 210 grams of protein a day,” Swank said. She also mentioned that she had to consume 60 egg whites per day, and when that proved too difficult, she had to drink them. And to keep the muscle on, she would get up and drink protein shakes in the middle of the night.