You probably already know that a scalpel is a tool used by a surgeon to make precise incisions into a patient. The US Navy's SCALPEL is just as precise - but it's a bomb. SCALPEL stands for Small Contained-Area Laser Precision Energetic Load.
Boiling all of that down into layman's terms, this is basically a bomb guided by laser technology. A SCALPEL can land in an urban location and take out a target without causing widespread damage to the area around it.