We warned you that some of the stories on our list are sad, and we can't help but feel sorry for everything that Amanda Bynes has been through. As a child actress, she was a hit with audiences on 'All That' and when she grew up into a beautiful young woman she seemed to have the world at her feet, with her own self-titled TV show. When it went wrong, though, it went badly wrong.
Bynes developed mental health issues, and also substance abuse issues, with the two things combining together to devastating effect. An increasingly unstable Bynes caused worry among her fanbase when she began posting bizarre Tweets on social media, and she ultimately ended up in rehab. She's now mentally and physically in a better place, but it's likely that her career in the public eye is over.