When people struggle with mental health or substance abuse issues, they're generally deserving of support and understanding. Regrettably, that isn't always the case, and it's harder to provide that support when someone is behaving badly because of their issues. In the sad case of Amanda Bynes, her problems brought her career to a crashing halt. She's been arrested for driving under the influence multiple times, and she was ultimately placed under a mental-health evaluation hold in 2013 after starting a fire in a stranger's driveway.
Bynes is doing a lot better these days. She's not yet returned to acting, but is believed to have been sober for four years, and has apologized profusely to all the people she hurt and upset when she was in the thick of her addiction. She's gone back to school, and is studying for a degree in product marketing with the intention of opening a fashion line.