Super-active singer, actor and activist says there's no special secret or method as to why her and her husband had a second child when she was 41; they were simply 'very attracted to each other', making the interesting observation that they were 'not machines or biological experiments', which seems to suggest that she's opposed to using artificial methods of conception.
As with some of the other women on the list, Milano sounds like she decided that her late thirties and early forties were simply the correct time for her to start having children; she'd had, in her own words, 'enough ladies lunches and shopping days', and was ready for something new in her life. In short, it sounds like she was just having too much fun to settle down and bring up a family until she did. There's nothing wrong with that!