Only the second woman in history (can you name the first?) to have been wife to one US President and mother to another, Barbara Bush passed away at the age of 92 in April of this year. She had been battling a number of health problems in recent years, including heart disease. She finally decided that enough was enough, and that she'd like to die peacefully in her own home, which she did.
Bush spent her time as first lady campaigning strongly for boosting literacy rates among America's young, with the belief that education was the biggest barrier many young Americans faced to better career prospects. Aside from that, unlike the accusations leveled at some of her predecessors and successors, she largely stayed out of politics, once being quoted as saying of her husband, "I don't fool around with his office, and he doesn't fool around with my household".