11. Sara Gilbert

After doing a bit of television commercial work as a child, Sara Gilbert really hit the big time with a regular acting gig. She managed to land a role on the hit comedy sitcom, Roseanne, and ended up staying for the entire nine-year run. She was just 13 years old when she started playing Darlene Conner, the middle child known for her biting sarcasm.

Since her days on Roseanne, Gilbert has enjoyed a prosperous career as a TV actor. She has appeared on The Simpsons, Will & Grace, 24, Private Practice, and ER, amongst others. More recently, she has appeared on Big Bang Theory and has been a co-host on The Talk, for which she won a Daytime Emmy Award. She is now starring as Darlene Conner again in the 2018 revival series of Roseanne.

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