Franklin D. Roosevelt was the 32nd President of the United States of America, and served in the office for a longer period than would be permitted under current rules. He took up his seat in the Oval Office in March 1933, and didn't leave it again until April 1945. What made Roosevelt especially remarkable is that he'd suffered a disease which had rendered him unable to walk, but had managed to convince most of the world that he could. He could 'walk' short distances by using a cane and an iron brace and swiveling his hips, and in other cases, his aides would simply carry him by his elbows.
Even in this picture, he may have been convincing people that he was feeling better than he actually was. It was taken on April 11th, 1945. By the following morning, he'd passed away after suffering a huge brain hemorrhage.