Garry Shandling was, for a long time, one of America's best-known comedians and television presenters. He had his own self-titled show, but he was arguably better known for 'the Larry Sanders' show, which he starred in across from Kathy Griffin. Perhaps fittingly, it was with Griffin that he had his last known photograph take - although he wouldn't have known it at the time.
Shandling suffered from a heart condition which meant that his life was always in a degree of danger, although it was believed he was controlling it with medication. On March 24th, 2016, Shandling suddenly collapsed at home and was rushed to a hospital, but was beyond medical help. He'd suffered a pulmonary embolism, and passed away at the age of 66. Hauntingly, this picture was taken just four days prior. He didn't have the look of someone at death's door.