We're going to have to warn you upfront: the tale of Alexis Arquette is not a happy one. But before we get to the tragedy, let's take you through her early life and the start of a brilliant career. Most people would have heard the Arquette name before, and with good reason. They're an entire family of solid Hollywood actors, with each sibling - Rosanna, Richmond, Patricia, Alexis, and David - sharing time on both big and small screen.
Born in 1969, Alexis (born Robert) was just as talented as the rest. Playing roles in close to a hundred films and TV shows - from Friends to Pulp Fiction to Xena - Alexis lit up the screen wherever she went. She also knew she was different from the norm early on, with her female alter ego Eva Destruction often making appearances in public. By 2004, she had decided: she would take the plung and get gender reassignment, officially making her a woman.